Publications

34. Mayampurath A*, Ramesh S*, Michael D, Liu L, Feinberg N, Granger M, Naranjo A, Cohn SL, Volchenboum SL, Applebaum MA. Predicting response to chemotherapy in patients with newly diagnosed neuroblastoma: a report from the International Neuro­­blastoma Risk Group. JCO Clin Cancer Inform. 2021; 5:1181-1188. PMID: 34882497. PMCID: PMC8812615. *Denotes co-first authors.

33. Balyasny S, Lee SM, Desai AV, Volchenboum,SL, Naranjo A, Park JR, London WB, Cohn SL, Applebaum MA. Association between participation in clinical trials and overall survival among children with intermediate- or high-risk neuroblastoma. JAMA Netw Open. 2021; 1;4(7):e2116248. PMID: 34236408. PMCID: PMC8267607.

32. Ramesh S, Chokkara S, Shen T, Major A, Volchenboum SL, Mayampurath A, Applebaum MA. Applications of artificial intelligence in pediatric oncology: A systematic review. JCO Clin Cancer Inform. 2021; 5:1208-1219. PMID: 34910588. PMCID: PMC8812636.

31. Barr EK, Laurie K, Wroblewski K, Applebaum MA, Cohn SL. Association between end-induction response according to the revised International Neuroblastoma Response Criteria (INRC) and outcome in high-risk neuroblastoma patients. Pediatr Blood Cancer. 2020; e28390. PMID: 32710697. PMCID: PMC7722196.

30. Schienda J*, Church AJ*, Corson LB, Decker B, Clinton CM, Manning DK, Imamovic-Tuco A, Reidy D, Strand GR, Applebaum MA, Bagatell R, DuBois SG, Glade-Bender JL, Kang W, Kim A, Laetsch TW,  Macy ME, Maese L, Pinto N, Sabnis AJ, Schiffman JD, Colace SI, Volchenboum SL, Weiser DA, Nowak JA, Lindeman NI, Janeway KA, Crompton BD, Kamihara J. Germline sequencing improves tumor-only sequencing interpretation in a precision genomic study of patients with pediatric solid tumor. JCO Precis Oncol. 2021; 5:1840-1852. PMID: 34964003. PMCID: PMC8710335. *Denotes co-first authors.

29. Siddiqui A, Pinto N, Applebaum MA, Mak GZ, Cunningham JM, LaBelle JL, Nassin ML. The addition of autologous stem cell transplantation to neoadjuvant chemotherapy, radiation, and HIPEC for patients with unresectable desmoplastic small round cell tumor: a single center case series. Int J Surg Onc. 2020; 5(6):e95. PMID: 35321405. PMCID: PMC8939842.

28. Sokol E, Desai AV, Applebaum MA, Valteau-Couanet D, Park JR, Pearson ADJ, Schleiermacher G, Irwin MS, Hogarty M, Naranjo A, Volchenboum S, Cohn SL, London WB. Reply to K Beiske et al. J Clin Oncol. 2020; 38(31):3720-3721. PMID: 32931402.

27. Sokol E, Desai AV, Applebaum MA, Shimada H, Valteau-Couanet D, Park JR, Pearson AD, Schleiermacher G, Irwin M, Hogarty M, Naranjo A, Volchenboum S, Cohn SL, London WB. Age, Diagnostic Category, Tumor Grade, and Mitosis-Karyorrhexis Index Are Independently Prognostic of Outcome in Neuroblastoma: An International Neuroblastoma Risk Group (INRG) project. J Clin Oncol. 2020. DOI:10.1200/JCO.19.03285. PMID: 32315273. PMCID: pending.

26. Gerstle K, Tanager K, Hegde S, Chung JH, Hussain AN, Applebaum MA, Dyamenahalli U. Pleuroparenchymal Fibroelastosis in an 8 Year Old Treated for Neuroblastoma. Pediatr Pulmonol. 2020; 3:E1-E4. PMID: 31944579. PMCID: PMC7036268.

25. Applebaum MA*, Barr EK*, Karpus J*, West-Syzmanski DC*, Olivia M, Sokol EA, Zhang S, Zhang Z, Zhang W, Chlenski A, Salwen HR, Wilkinson E, Dobratic M, Grossman RL, Godley LA, Stranger BE, He C, Cohn SL. 5-hydroxymethylcytosine profiles in circulating cell-free DNA associate with disease burden in children with neuroblastoma. Clinical Cancer Research. 2020; 20(6):1309-17. PMID: 31852832. PMCID: PMC7073281. *Denotes co-first authors.

24. Weiser DA*, West-Szymanski DC*, Fraint E*, Weiner S, Rivas MA, Zhao CWT, He C, Applebaum MA. Progress toward liquid biopsies in pediatric solid tumors. Cancer Metastasis Rev. 2019; 4:553-571. PMID: 31836951. PMCID: PMC6995761. *Denotes co-first authors.

23. Pudela C, Balyasny S, Applebaum MA. Peripheral neuroblastic tumours (Neuroblastoma, Ganglioneuroblastoma, Ganglioneuroma). Atlas Genet Cytogenet Oncol Haematol. 2020; 24(7):284-290. PMID: 32296467. PMCID: PMC7158874.

22. Applebaum H, Applebaum MA. A conversation with my personal oncologist. Fam Syst Health. 2019; 37(4):344-346. PMID: 31815516. PMCID: PMC6903692.

21. Applebaum MA*, Barr E*, Karpus J*, Nie J*, Zhang Z, Armstrong AE, Gosiengfiao YC, Uppal S, Sukhanova M, Zhang W, Chlenski A, Salwen HR, Wilkinson E, Dobratic M, Stranger BE, Godley LA, He C, Cohn SL. The epigenetic mark 5-hydroxymethylcytosine identifies activated oncogeneic pathways and serves as a biomarker for risk classification in neuroblastoma. JCO Precis Oncol. DOI 10.1200/PO.18.00402. PMID: pending. PMCID: pending. * Denotes co-first authors.

20. Chlenski A, Park C, Dobratic M, Salwen HR, Budke B, Park JH, Miller R, Applebaum MA, Wilkinson E, Nakamura Y, Connell PP, Cohn SL. Maternal Embryonic Leucine Zipper Kinase (MELK), a potential therapeutic target for neuroblastoma. Mol Cancer Ther. 2019 Jan 23. PMID: 30674566. PMCID: 6398941.

19. Barr EK, Applebaum MA. Genetic Predisposition to Neuroblastoma. Children (Basel). 2018 Aug 31;5(9). doi: 10.3390/children5090119. Review. PubMed PMID: 30200332; PubMed Central PMCID: PMC6162470.

18. Cowan M, Suntum T, Olivas AD, Perpich M, Applebaum MA, Lastra RR, Yamada SD. Second primary rhabdomyosarcoma of the uterine cervix presenting with synchronous ovarian Sertoli-Leydig cell tumor: An illustrative case of DICER1 syndrome. Gynecol Oncol Rep. 2018 Aug;25:94-97. doi: 10.1016/j.gore.2018.06.008. eCollection 2018 Aug. PubMed PMID: 30014022; PubMed Central PMCID: PMC6019406.

17. Hungate EA*, Applebaum MA*, Skol AD, Vaksman Z, Diamond M, McDaniel L, Volchenboum SL, Stranger BE, Maris JM, Diskin SJ, Onel K, Cohn SL. Evaluation of Genetic Predisposition for MYCN-Amplified Neuroblastoma. J Natl Cancer Inst.2017 Oct 1;109(10). doi: 10.1093/jnci/djx093. PubMed PMID: 29117357; PubMed Central PMCID: PMC6279278. * Denotes co-first author.

16. Applebaum MA, Desai AV, Glade Bender JL, Cohn SL. Emerging and investigational therapies for neuroblastoma. Expert Opin Orphan Drugs. 2017;5(4):355-368. doi: 10.1080/21678707.2017.1304212. Epub 2017 Mar 17. PubMed PMID: 29062613; PubMed Central PMCID: PMC5649635.

15. Applebaum MA, Vaksman Z, Lee SM, Hungate EA, Henderson TO, London WB, Pinto N, Volchenboum SL, Park JR, Naranjo A, Hero B, Pearson AD, Stranger BE, Cohn SL, Diskin SJ. Neuroblastoma survivors are at increased risk for second malignancies: A report from the International Neuroblastoma Risk Group Project. Eur J Cancer. 2017 Feb;72:177-185. doi: 10.1016/j.ejca.2016.11.022. Epub 2016 Dec 26. PubMed PMID: 28033528; PubMed Central PMCID: PMC5258837.

14. Chlenski A, Dobratic M, Salwen HR, Applebaum M, Guerrero LJ, Miller R, DeWane G, Solomaha E, Marks JD, Cohn SL. Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids. Oncotarget. 2016 Nov 22;7(47):77696-77706. doi: 10.18632/oncotarget.12773. PubMed PMID: 27776337; PubMed Central PMCID: PMC5363614.

13. Applebaum MA*, Jha AR*, Kao C, Hernandez KM, DeWane G, Salwen HR, Chlenski A, Dobratic M, Mariani CJ, Godley LA, Prabhakar N, White K, Stranger BE, Cohn SL. Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients. Oncotarget. 2016 Nov 22;7(47):76816-76826. doi: 10.18632/oncotarget.12713. PubMed PMID: 27765905; PubMed Central PMCID: PMC5340231. * Denotes co-first author.

12. Pinto N, Mayfield JR, Raca G, Applebaum MA, Chlenski A, Sukhanova M, Bagatell R, Irwin MS, Little A, Rawwas J, Gosiengfiao Y, Delattre O, Janoueix-Lerosey I, Lapouble E, Schleiermacher G, Cohn SL. Segmental Chromosomal Aberrations in Localized Neuroblastoma Can be Detected in Formalin-Fixed Paraffin-Embedded Tissue Samples and Are Associated With Recurrence. Pediatr Blood Cancer. 2016 Jun;63(6):1019-23. doi: 10.1002/pbc.25934. Epub 2016 Feb 10. PubMed PMID: 26864375; PubMed Central PMCID: PMC5109976.

11. Applebaum MA, Cohn SL. Surveillance of Childhood Cancer Survivors: A Lifelong Affair. J Clin Oncol. 2015 Nov 1;33(31):3531-2. doi: 10.1200/JCO.2015.62.7703. Epub 2015 Aug 10. PubMed PMID: 26261248.

10. Pinto NR, Applebaum MA, Volchenboum SL, Matthay KK, London WB, Ambros PF, Nakagawara A, Berthold F, Schleiermacher G, Park JR, Valteau-Couanet D, Pearson AD, Cohn SL. Advances in Risk Classification and Treatment Strategies for Neuroblastoma. J Clin Oncol. 2015 Sep 20;33(27):3008-17. doi: 10.1200/JCO.2014.59.4648. Epub 2015 Aug 24. Review. PubMed PMID: 26304901; PubMed Central PMCID: PMC4567703.

9. Applebaum MA, Henderson TO, Lee SM, Pinto N, Volchenboum SL, Cohn SL. Second malignancies in patients with neuroblastoma: the effects of risk-based therapy. Pediatr Blood Cancer. 2015 Jan;62(1):128-33. doi: 10.1002/pbc.25249. Epub 2014 Sep 23. PubMed PMID: 25251613; PubMed Central PMCID: PMC4237647.

8. Applebaum MA, Skol AD, Bond EE, Overholtzer M, Bond GL, Onel K. Radiation-induced apoptosis varies among individuals and is modified by sex and age. Int J Radiat Biol. 2014 Oct;90(10):903-8. doi: 10.3109/09553002.2014.925603. Epub 2014 Jun 25. PubMed PMID: 24882388; PubMed Central PMCID: PMC4222525.

7. Applebaum MA, Thomas DG, Hembrough T, Burrows J, Horvai AE, Lawlor ER, DuBois SG. Comparative evaluation of strategies for quantifying signaling pathway proteins in Ewing sarcoma. Appl Immunohistochem Mol Morphol. 2014 Sep;22(8):593-9. doi: 10.1097/PAI.0b013e3182a8d4bb. PubMed PMID: 24590121; PubMed Central PMCID: PMC4148473.

6. Applebaum MA, Goldsby R, Neuhaus J, DuBois SG. Clinical features and outcomes in patients with secondary Ewing sarcoma. Pediatr Blood Cancer. 2013 Apr;60(4):611-5. doi: 10.1002/pbc.24251. Epub 2012 Jul 27. PubMed PMID: 22847990; PubMed Central PMCID: PMC3488141.

5. Applebaum MA, Lawson EF, von Scheven E. Perception of transition readiness and preferences for use of technology in transition programs: teens’ ideas for the future. Int J Adolesc Med Health. 2013;25(2):119-25. doi: 10.1515/ijamh-2013-0019. PubMed PMID: 23740658.

4. Applebaum MA, Goldsby R, Neuhaus J, DuBois SG. Clinical features and outcomes in patients with Ewing sarcoma and regional lymph node involvement. Pediatr Blood Cancer. 2012 Oct;59(4):617-20. doi: 10.1002/pbc.24053. Epub 2011 Dec 19. PubMed PMID: 22184129; PubMed Central PMCID: PMC3310932.

3. Applebaum MA, Sambrano E, Lee S, Goldsby R, Matthay KK, DuBois SG. Evaluation of plasma annexin V levels in children and young adults with solid tumors. Int J Biol Markers. 2012 Jul 19;27(2):e164-6. doi: 10.5301/JBM.2012.9288. PubMed PMID: 22610756; PubMed Central PMCID: PMC4222526.

2. Lawson EF, Hersh AO, Applebaum MA, Yelin EH, Okumura MJ, von Scheven E. Self-management skills in adolescents with chronic rheumatic disease: A cross-sectional survey. Pediatr Rheumatol Online J. 2011 Dec 6;9(1):35. doi: 10.1186/1546-0096-9-35. PubMed PMID: 22145642; PubMed Central PMCID: PMC3254592.

1. Applebaum MA, Worch J, Matthay KK, Goldsby R, Neuhaus J, West DC, Dubois SG. Clinical features and outcomes in patients with extraskeletal Ewing sarcoma. Cancer. 2011 Jul 1;117(13):3027-32. doi: 10.1002/cncr.25840. Epub 2011 Jan 10. PubMed PMID: 21692057; PubMed Central PMCID: PMC3135782.