* Dodiya HB, Lutz HL*, Weigle IQ*, Patel P, Michalkiewicz J, Roman-Santiago CJ, Zhang CM, Liang Y, Srinath A, Zhang X, Xia J, Olszewski M, Zhang X, Schipma MJ, Chang EB, Tanzi RE, Gilbert JA, Sisodia SS (2022). Gut microbiota-driven brain Ab amyloidosis in mice requires microglia. J Exp Med. 219 (1): e20200895.

* Zhang X, Zhang CM, Prokopenko D, Liang Y, Zhen SY, Weigle IQ, Han W, Aryal M, Tanzi RE, Sisodia SS (2021). An APP ectodomain mutation outside of the Aβ domain promotes Aβ production in vitro and deposition in vivo. J Exp Med. 7;218(6):e20210313.

* Dodiya HB, Frith M, Sidebottom A, Cao Y, Koval J, Chang E, Sisodia SS (2020). Synergistic depletion of gut microbial consortia, but not individual antibiotics, reduces amyloidosis in APPPS1-21 Alzheimer’s transgenic mice. Sci Rep.18;10(1):8183.

* Zhang X, Zhang C, Prokopenko D, Liang Y, Han W, Tanzi RE, Sisodia SS (2020). Negative evidence for a role of APH1B T27I variant in Alzheimer’s disease. Hum Mol Genet. 15;29(6):955-966.

* Ortega-Martinez S, Palla N, Zhang X, Lipman E, Sisodia SS (2019). Deficits in Enrichment-Dependent Neurogenesis and Enhanced Anxiety Behaviors Mediated by Expression of Alzheimer’s Disease-Linked Ps1 Variants Are Rescued by Microglial Depletion. J Neurosci. 21;39(34):6766-6780.

* Dodiya HB, Kuntz T, Shaik SM, Baufeld C, Leibowitz J, Zhang X, Gottel N, Zhang X, Butovsky O, Gilbert JA, Sisodia SS (2019). Sex-specific effects of microbiome perturbations on cerebral Aβ amyloidosis and microglia phenotypes. J Exp Med.1;216(7):1542-1560.

* Minter MR, Hinterleitner R, Meisel M, Zhang C, Leone V, Zhang X, Oyler-Castrillo P, Zhang X, Musch MW, Shen X, Jabri B, Chang EB, Tanzi RE, Sisodia SS (2017). Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APP_SWE/PS1_ΔE9 murine model of Alzheimer’s disease. Sci Rep. 5;7(1):10411.

* Minter MR, Zhang C, Leone V, Ringus DL, Zhang X, Oyler-Castrillo P, Musch MW, Liao F, Ward JF, Holtzman DM, Chang EB, Tanzi RE, Sisodia SS (2016). Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer’s disease. Sci Rep. 6:30028

* Zhang X, Sullivan E, Scimeca M, Wu X, Li YM, Sisodia SS (2016). Evidence That the “Lid” Domain of Nicastrin Is Not Essential for Regulating γ-Secretase Activity. J Biol Chem. 25;291(13):6748-53.

* Veeraraghavalu K, Zhang C, Zhang X, Tanzi RE, and Sisodia SS (2014). Age-dependent, non-cell autonomous deposition of amyloid from synthesis of Aβ by cells other than excitatory neurons. J. Neuroscience, 34:3668-73

* Veeraraghavalu K. and Sisodia SS (2013). Mutant presenilin 1 expression in excitatory neurons impairs enrichment-mediated phenotypes of adult hippocampal progenitor cells. Proc. Natl. Acad. Sci USA, 110:9148-53

* Zhang X, Hoey RJ, Lin G, Koide A, Leung B, Ahn K, Dolios G, Paduch M, Ikeuchi T, Wang R, Li Y, Koide S and Sisodia SS (2012). Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies. Proc. Natl. Acad. Sci. USA, 109:8534-9

* Choi S, Veeraraghavalu K, Lazarov O, Marler S, Ransohoff RM, Ramirez JM and Sisodia SS (2008). Non-Cell-Autonomous Effects of Presenilin 1 Variants on Enrichment-Mediated Hippocampal Progenitor Cell Proliferation and Differentiation. Neuron, 59, 568-580

* Lazarov O, Pigino G, Morfini GA, Gadadhar A, Chen X, Robinson J, Ho H,Brady ST, Sisodia SS (2007). Impairments in Fast Axonal Transport and Motor Neuron Deficits in Transgenic Mice Expressing FAD-Linked mutant PS1. J. Neuroscience, 27: 7011-7020.

* Lazarov O, Robinson J, Tang Y, Hairston IS, Korade-Mirnics Z, Lee V, Hersh LB, Sapolsky RM, Mirnics K, and Sisodia SS (2005). Environmental Enrichment Reduces A Levels and Amyloid Deposition in Transgenic Mice. Cell, 120, 701-713

* Lazarov O, Lee M, Peterson DA, Sisodia SS (2002). Evidence that Synaptically Released beta-Amyloid Accumulates as Extracellular Deposits in the Hippocampus of Transgenic Mice. J. Neurosci, 15:9785-93

* Buxbaum JD, Thinakaran G, Koliatsos V, O’Callahan J, Slunt HH, Price DL and Sisodia SS (1998). Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path. J. Neurosci. 18:9629-9637

* Borchelt DR, Ratovitski T, Van Lare J, Lee MK, Gonzales VB, Jenkins NA, Copeland NG, Price DL and Sisodia SS (1997). Accelerated amyloid deposition in the brains of transgenic mice co-expressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19: 939-945

* Wong PC, Zheng H, Chen H, Becher MW, Sirinathsinghji DJS, Trumbauer ME, Chen HY, Price DL, Van der Ploeg LHT and Sisodia SS (1997) Presenilin 1 is required for Notch1 and Dll1 expression in the paraxial mesoderm. Nature 387: 288-292

* von Koch CS, Zheng H, Chen H, Trumbauer M, Thinakaran G, Van der Ploeg LHT, Price DL and Sisodia SS (1997). Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice. Neurobiol. Aging 18: 661-669

* Borchelt DR, Thinakaran G, Eckman CB, Lee MK, Davenport F, Ratovitsky T, Prada C-M, Kim G, Seekins S, Yager D, Slunt HH, Wang R, Seeger M, Levey AI, Gandy SE, Copeland NG, Jenkins NA, Price DL, Younkin SG and Sisodia SS (1996). Familial Alzheimer’s disease-linked presenilin 1 variants elevate Aβ1-42/1-40 ratio in vitro and in vivo. Neuron 17: 1005-1013

* Thinakaran G, Borchelt DR, Lee MK, Slunt HH, Spitzer L, Kim G, Ratovitski T, Davenport F, Nordstedt C, Seeger M, Hardy J, Levey AI, Gandy SE, Jenkins N, Copeland N, Price DL and Sisodia SS (1996). Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron 17: 181-190

* Sisodia SS, Koo EH, Hoffman PN, Perry G and Price DL (1993). Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system. J. Neurosci. 13: 3136-3142, 1993.

* Sisodia SS (1992). ß-amyloid precursor protein cleavage by a membrane-bound protease. Proc. Natl. Acad. Sci. USA 89: 6075-6079

Complete List of Published Work: http://www.ncbi.nlm.nih.gov/sites/myncbi/sangram.sisodia.1/bibliography/41155520/public/?sort=date&direction=ascending