Du, X., et al. (2020) Loss-of-function BK channel mutation causes impaired mitochondria and progressive cerebellar ataxia. PNAS.
Du, X., et al. (2019) α1ACT is essential for survival and early cerebellar programming in a critical neonatal window. Neuron. Online Publication
Hejazi Pastor, DP., et al. (2018) Targeting the CACNA1A IRES as a Treatment for Spinocerebellar Ataxia Type 6. Cerebellum. 2018 Feb;17(1):72-77
Du, X., et al. (2018) Spinocerebellar Ataxia Type 6: Molecular Mechanisms and Calcium Channel Genetics. Adv Exp Med Biol. 2018;1049:147-17
Miyazaki, Y., et al. (2016) An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron. Sci Transl Med 8, 347ra394
Du, X., et al. (2013) A second cistron in the CACNA1A gene encodes a transcription factor that mediates cerebellar development and SCA6. Cell 154, 118-133
Tsou, WL., et al. (2015) DnaJ-1 and karyopherin α3 suppress degeneration in a new Drosophila model of Spinocerebellar Ataxia Type 6. Hum Mol Genet. 24(15):4385-96
Reviews
Karginov, TA., et al. (2017) Mammalian Polycistronic mRNAs and Disease. Trends in Genetics. 33(2):129–142
Du, X., et al. (2014) Revelations from a bicistronic calcium channel gene. Cell Cycle 13, 875-876
