Human Tissue Resource Center

About

The Human Tissue Resource Center (HTRC) is a pathology-based, CAP-accredited core facility directed by Dr. Mark Lingen. The effective procurement, storage, distribution, and analysis of human biospecimens are of critical importance to biomedical research. The HTRC provides investigators with a centralized infrastructure to optimize the efficiency and costs related to research involving human biospecimens. In this way, the core provides a coordinated, centralized, and dedicated program for the procurement, processing, dispersing, and assessment of all types of biospecimens. Thus, duplication of personnel, equipment, and information systems is avoided, and coordination of activities is assured. The HTRC is comprised of four integrated subcores: biospecimen bank (BSB), digital pathology, laser capture microdissection (LCM), and histology (which includes immunohistochemistry (IHC) and tissue microarray (TMA)).

The HTRC offers efficient and cost-effective options for:

  • Biobanking of solid tissues, lymphocytes and bodily fluids including serum, plasma, saliva, and urine
  • Pathological verification and analysis of tissue samples
  • Histological services including routine tissue formalin fixation, processing, paraffin embedding, microtomy, H&E staining, in situ hybridization, and immunostaining
  • Tissue microarray (TMA) fabrication
  • Laser capture microdissection (LCM)
  • Quantitative image analysis of immunohistochemistry on conventional and tissue microarray sections, including tissue scoring, rare event detection, microvascular density counting, ploidy analysis, integrated optical density analysis, and tissue microarray scoring.

The core may be identified in publications as The University of Chicago Human Tissue Resource Center (RRID:SCR_019199).

Human Tissue Resource Center

5812 South Ellis Avenue
Rooms P524, P612, P616, P630
Chicago, IL 60637

(773) 834-4593

TissueBank@bsd.uchicago.edu
Histology@bsd.uchicago.edu
DigitalPathology@bsd.uchicago.edu

7:30am – 5:00pm, Monday-Friday

Dr. Mark Lingen
Faculty Director, HTRC
mark.lingen@uchospitals.edu
773.702.5548

Terri Li
Technical Director – Histology
tli1@bsd.uchicago.edu
773.702.9051

Rachel Poon
Technical Director – Biobank
rpoon@bsd.uchicago.edu
773.834.4593

A list of all HTRC’s contacts is available in the Staff Directory.

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