Research Articles

Chen J and Chen ZJ. PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation. Nature. 2018 Dec. PMID: 30487600

• Research Highlight in Nature Reviews Immunology.
• Research Highlight in Cell Research.
• Recommendations on Faculty of 1000.

Cai X, Chen J, Xu H, Liu S, Jiang QX, Halfmann R, Chen ZJ. Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation. Cell. 2014 Mar. PMID: 24630723

Liu S*, Chen J*, Cai X, Wu J, Chen X, Wu YT, Sun L, Chen ZJ. MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. eLife. 2013 Aug. PMID: 23951545 (*co-first authors)

Skaug B, Chen J, Du F, He J, Ma A, Chen ZJ. Direct, noncatalytic mechanism of IKK inhibition by A20. Mol Cell. 2011 Nov. PMID: 22099304

 

Reviews

Mullins B and Chen J. NLRP9 in Innate Immunity and Inflammation. Immunology. 2020 Dec 6. PMID: 33283292

Tan X, Sun L, Chen J, Chen ZJ. Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids. Annu Rev Microbiol. 2018 Sep. PMID: 30200854

Chen J and Chen ZJ. Regulation of NF-κB by ubiquitination. Curr Opin Immunol. 2013 Feb. PMID: 23312890