Publications

Preprints:

1. Nguyen LC, Yang D, Nicolaescu V, Best TJ, Ohtsuki T, Chen SN, Friesen JB, Drayman N, Mohamed A, Dann C, Silva D, Gula H, Jones KA, Millis JM, Dickinson BC, Tay S, Oakes SA, Pauli GF, Meltzer DO, Randall G, Rosner MR. Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response. 2021 bioRxiv [preprint].  https://www.biorxiv.org/content/10.1101/2021.03.10.432967v1

 

2. Walter S ,Franke V ,Drayman N , Wyler E , Tay S, Landthaler M, Akalin A, Ensser A, Full F. Herpesviral induction of germline transcription factor DUX4 is critical for viral gene expression. 2021 bioRxiv [preprint]. https://www.biorxiv.org/content/10.1101/2021.03.24.436599v1

 

3. Phan V*, Van Gent M*, Drayman N*, Basu A, Gack MU, Tay S. Fixed single-cell RNA sequencing for understanding virus infection and host response. bioRxiv [preprint] . 302232 (2020). https://doi.org/10.1101/2020.09.17.302232.

* co-first authors

 

4. Patel P, Drayman N, Liu P, Bilgic M, Tay S. Deep learning reveals hidden variables underlying NF-κB activation in single cells. bioRxiv [Preprint] 687848 (2019). doi:10.1101/687848

 

Peer Reviewed:

5. Drayman N, DeMarco J, Jones K, Azizi S, Froggatt H, Tan K, Maltseva N, Chen S, Nicolaescu V, Dvorkin S, Furlong K, Kathayat R, Firpo M, Mastrodomenico V, Bruce E, Schmidt M, Jedrzejczak R, Muñoz-Alía M, Schuster B, Nair V, Han K, O’Brien A, Tomatsidou A, Meyer B, Vignuzzi M, Missiakas D, Botten J, Brooke C, Lee H, Baker S, Mounce B, Heaton N, Severson W, Palmer K, Dickinson B, Jaochimiak A, Randall G, and Tay S. Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2. 2021 July 20.

 

6. Morris A, McCorkindale W, Consortium TCM, Drayman N, Chodera JD, Tay S, London N, Lee AA. Discovery of SARS-CoV-2 main protease inhibitors using a synthesis-directed de novo design model. Chem Commun (Camb). 2021 May 19.

 

7. Lin J, Jordi C, Son M, Van Phan H, Drayman N, Abasiyanik MF, Vistain L, Tu HL, Tay S. Ultra-sensitive digital quantification of proteins and mRNA in single cells. Nat Commun. 2019 Aug 7;10(1):3544. doi: 10.1038/s41467-019-11531-z. PMCID: PMC6685952.

 

8. Drayman N, Patel P, Vistain L, Tay S. HSV-1 single-cell analysis reveals the activation of anti-viral and developmental programs in distinct sub-populations. Elife. 2019 May 15;8. pii: e46339. doi: 10.7554/eLife.46339.

 

9. Tomer E, Cohen EM, Drayman N, Afriat A, Weitzman MD, Zaritsky A, Kobiler O. Coalescing replication compartments provide the opportunity for recombination between coinfecting herpesviruses. FASEB J. 2019 May 20:fj201900032R. doi: 10.1096/fj.201900032R.[Epub ahead of print].

 

10. Drayman N, Karin O, Mayo A, Danon T, Shapira L, Rafael D, Zimmer A, Bren A, Kobiler O and Alon U. Dynamic Proteomics of Herpes Simplex virus infection. Nov 2017, mBio, 8:e01612-17.

 

11. Drayman N. Observed High Coinfection Rates Seem To Be a Result of Overlapping Plaques. Oct 2017, mBio, 2017. 8:e01000-17.

 

12. Drayman N, Ben-Nun-Shaul O, Butin-Israeli V, Srivastava R, Rubinstein AM, Mock CS, Elyada E, Ben-Neriah Y, Lahav G, Oppenheim A. p53 acts in host defense against SV40 infection by repressing T-antigen expression. Oncotarget, 2016. Aug 16;7(33):52643-52660.

 

13. Bauman Y, Drayman N, Ben-Nun-Shaul O, Vitenstein A, Yamin R,Ophir Y, Oppenheim A and Mandelboim O. Downregulation of the stress-induced ligand ULBP1 following SV40 infection confers viral evasion from NK cell cytotoxicity. Oncotarget. 2016 Mar 29;7(13):15369-81.

 

14. Glick Y, Ben-Ari Y, Drayman N, et al. Pathogen Receptor Discovery with a Microfluidic Human Membrane Protein Array. PNAS, 2016 Apr 19;113(16):4344-9.

 

15. Arbelle A, Drayman N, Bray M, Alon U, Carpenter A and Riklin Raviv T. Analysis of High-throughput Microscopy Videos: Catching Up with Cell Dynamics. International Conference of Medical Image computing and Computer Assisted Intervention (MICCAI 2015), pages 218-225.

 

16. Drayman N, Glick Y, Zer H, Zlotnick A, Gerber D, Schueler-Furman O and Oppenheim A. Pathogens use structural mimicry of native host ligands as a mechanism of host recognition. Cell Host & Microbe. 2013 Jul 17;14(1):63-73.

 

17. Stergiou L, Bauer M, Mair W, Bausch-Fluck D, Drayman N, Wollscheid B, Oppenheim A and Pelkmans L. Integrin-Mediated Signaling Induced by Simian Virus 40 Leads to Transient Uncoupling of Cortical Actin and the Plasma Membrane. PLoS One. 2013;8(2):e55799.

 

18. Kobiler O, Drayman N, Butin-Israeli V and Oppenheim A. Virus strategies for passing the nuclear envelope barrier. Nucleus. 2012 Nov-Dec;3(6):526-39.

 

19. Drayman N and Oppenheim A. Rapid titration of viruses by flow cytometry. In: Current Protocols in Cell Biology, 2011 Jun; Chapter 26:Unit26.11.

 

20. Bauman Y, Nachmani D, Vitenshtein A, Tsukerman P, Drayman N, Stern-Ginossar N, Lankry D, Gruda R, Mandelboim O. An Identical miRNA of the Human JC and BK Polyoma Viruses Targets the Stress-Induced Ligand ULBP3 to Escape Immune Elimination. Cell Host & Microbe. 2011 Feb 17;9(2):93-102.

 

21. Drayman, N., Kler, S., Ben-Nun-Shaul, O., and Oppenheim, A. Rapid method for SV40 titration. J Virol Methods. 2010 Mar;164(1-2):145-7.

 

22. Butin-Israeli, V., Drayman, N., and Oppenheim, A. Host-virus interactions: SV40 infection triggers balanced network that includes apoptotic, survival and stress pathways. J Virol. 2010 Apr;84(7):3431-42.

 

23. Leiba, A., Drayman, N., Amsalem, Y., Aran, A., Weiss, G., Leiba, R., Schwartz, D., Levi, Y., Goldberg, A., and Bar-Dayan, Y. Establishing a high level of knowledge regarding bioterrorist threats in emergency department physicians: methodology and the results of a national bio-preparedness project. Prehosp Disaster Med. 2007 May-Jun;22(3):207-11