Welcome to the Piccirilli Lab

Our group is broadly interested in the chemistry and biochemistry of nucleic acids with particular emphasis on RNA and RNA catalysis. The laboratory integrates areas of organic chemistry, physical chemistry, enzymology and molecular biology to gain a fundamental understanding of nucleic acid structure and mechanisms of RNA catalysis. Using the principles and techniques of organic chemistry and molecular biology, we manipulate the structure of RNA molecules at precise locations in ways that are designed to answer very specific questions about biological function. With a team consisting of people trained in EPR, Optical Tweezers, Fluorescence spectroscopy, MRI and X-Ray Crystallography, protein engineering and Nucleic acid synthetic chemistry, we are equipped to take on varied challenges in RNA chemistry and biology.

Apply for Postdoc, Graduate and Undergraduate Positions
Please send a resume and a description of research accomplishments, research interests, and long-term goals. All inquires should be emailed to: jpicciri@uchicago.edu

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