The Rebay Lab uses the developing Drosophila eye, wing and heart to study how cell fates are specified and organized into functional tissues and organs. Our experimental approach is multidisciplinary, and incorporates molecular genetics, genomics, quantitative imaging, biochemistry and mathematical modeling. Current interests are focused on transcriptional networks and cellular mechanisms that regulate and stabilize the transition from uncommitted progenitor to specified fate. We also study the signaling mechanisms and tissue-level biomechanical properties that together drive terminal differentiation and morphogenesis.

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