Current Lab Members

Professor, Ben May Department for Cancer Biology and Department of Molecular Genetics and Cell Biology

Member: Graduate Program in Cell and Molecular Biology

Committee on Development, Regeneration and Stem Cell Biology

Committee on Genetics, Genomics and Systems Biology

UChicago Comprehensive Cancer Center                                                           UChicago Institute for Genomics and Systems Biology

Ph.D. Biology, Yale University 1993
B.A. Mathematics, Columbia University 1987

email

DRSB 2017

B.S. Universidad Nacional Mayor de San Marcos, Genetics & Biotechnology

The simplicity in design of the Notch signaling pathway belies exceptional complexity as Notch can perform a plethora of functions (proliferation, cell fate specification, morphogenesis, cell death, etc) in a context-dependent manner (across different tissues or in the same tissue at different timepoints/conditions). I’m interested in understanding how different factors can activate/inactivate Notch in a spatiotemporal manner to ensure its proper functioning. Currently, I study how the Abelson kinase regulates Notch trafficking and signaling.

Personal Background: Born and raised in Peru. Lived in Havana, Cuba and various cities in the US

Favorite gene/protein: Of course Notch, but I also like armadillo (B-cat).

Honorary titles: The wing person in the lab, master of learning new protocols (even if I have to teach myself).

DRSB 2019

BS in Biochemistry, University of Michigan, Ann Arbor

I’m interested in the cell biological mechanisms and regulatory signals that potentiate coordinated morphological changes across multiple cell types to give rise to a function organ.

Personal Background: Native Chicagoan.

Favorite Gene: Shavenbaby or Lavalamp

Favorite Paper: Canalization by Selection of de Novo Induced Mutations. Fanti et., al., Genetics (2017). This paper will either make you love or hate fly genetics.

Honorary Titles: I don’t think I’ve earned any honorary titles yet, but I’m sure that will change with time.

PhD, Institute of Developmental Biology, Moscow

I am broadly interested in the evolution and function of gene regulatory networks during development. My current projects focus on transvection and transcriptional-level feedback regulation during cell fate specification.

Publications: Wu et al., PLoS Genetics 2020

Personal Background: Born and raised in the Soviet Union, but have worked at the University of Chicago for a long long time.

Favorite Gene: Even-skipped (Eve)

Honorary Titles: Grand master of molecular biology and genetics.

Biochemistry Major, UChicago Class of 2024

I’m interested in how transcription factor signaling and protein interactions drive cell fate specification. My project focuses on determining how levels of the transcriptional repressor Yan and the activator Pnt are modulated during the transition from progenitor to more specific cell fate.

Personal Background: From Connecticut.

Favorite Gene: Boss

Honorary Titles: TBA