Nature Ecology and Evolution published our paper, “Multinucleotide mutations cause false inferences of lineage-specific positive selection.” The work was part of Aarti Venkat’s thesis, and it was especially fun to work with coauthor Matt Hahn, an expert in MNMs at Indiana University, on the paper. We found that the natural tendency of mutations to occur at adjacent sites causes codon-model selection tests to be strongly biased towards false positive results. In fact, under realistic genome-wide conditions, the number of genes with putative signatures of selection does not exceed the number of genes expected to return false positive results because of MNM-induced bias. The pdf is here, and a link is here here. Also, did I mention that I don’t intend to publish in this journal again until Springer-Nature provides an open access option?