Services
- Production of transgenic mice from injection through the F1 stage
- Standard strains: CD-1 outbred, C57Bl/6 inbred
- Almost all non-standard strains can be accommodated, including KO and transgenic models
- Embryonic Stem Cell Services
- Blastocyst injections
- NeoR Timed pregnant females for fibroblast feeder cells
- TgN(DR4)1Jae timed pregnant females for fibroblast feeder cells
- (drug resistant to G418, 6-thioguanine, puromycin, and hygromycin)
- Breeding of chimeric mice through the F1 stage
- ES Cell Lines Available:
- 129/S6
- C57B6/T
- B6-tyrC-2J (B6 white), B6-tyrC-2J /KSR
- C57BL6/J
- 129/X1
- Balb/CJ
- C3H
- Embryo aggregations
- Tail biopsies for genotyping
- Timed pregnant mice for embryo or newborn use
- Mouse breeding services and advice
- Rederivation of non-commercial mice (in conjunction with the ARC)
- ES cell culture services, including feeder production, ES cell targeting
- Gene construction for ES cell targeting
- Isogenic DNA for the preparation of ES cell constructs