Program

Monday, 5 June

14:30 – 15:00 Introductory Remarks

15:00 – 17:30 Session #1

15:00 – 15:30 Tobin Sosnick, Factors That Determine the Force Needed to Unfold a Membrane Protein in Silico Depend on the Pulling Direction and Spring Strength

15:30 – 16:00 Halima Mouhib, Modeling the molecular interactions that initiate secretion of autotransporter proteins across the bacterial outer membrane

16:00 – 16:15 Sebastien Mongrand, Unconventional protein anchoring and organization into Functional Nanodomains of the plant-specific protein REMORIN

16:15 – 16:45 Pierre Sens, Mechano-sensing through self assembly at the cell membrane: the example of caveolae

16:45 – 17:15 Jean-Baptiste Fournier, Protein clustering from multibody interactions and membrane tension

17:15 – 17:30 Discussion

17:30 – 19:00 Welcome Reception

Tuesday, 6 June

008:30 – 09:00 Welcome Coffee

09:00 – 12:30 Session #2

09:00 – 09:30 David Tareste, Role of the heptad repeat domains of Mitofusin in membrane fusion

09:30 – 10:00 Luca Monticelli, Birth of an organelle, in silico: molecular mechanism of lipid droplet budding

10:00 – 10:30 Coffee Break

10:30 – 10:45 Louis Bunel, Investigating lipid-cation interactions effect on SNARE-mediated membrane fusion

10:45 – 11:15 Andela Saric, The Original Curve: Reshaping of archaeal membranes

11:15 – 11:30 Burkhard Bechinger, Mechanism of action and lipid-mediated synergistic interactions of antimicrobial peptides

11:30 – 12:00 Pierre-Emmanuel Milhiet, Real-time imaging of membrane remodeling induced by septin oligomerization

12:00 – 12:15 Raphaelle Versini, Molecular dynamics based prediction of Fzo1 transmembrane domains structure

12:15 – 12:30 Discussion

12:30 – 13:30 Lunch

13:30 – 14:00 Mathilde Cambournac, CNRS Resources for Collaboration

14:00 – 16:15 Session #3

14:00 – 14:30 Benoit Roux, Emerging methodologies in computational studies of biological membranes

14:30 – 15:00 Eduardo Perozo, Prestin Conformational Dynamics and the Molecular Basis of the Cochlear Amplifier

15:00 – 15:15 Costanza Paternoster, Computational strategies for the dimerization of pore-forming toxin components on a model membrane

15:15 – 15:45 Laurent Catoire, Exploration of the dynamic interplay between lipids and membrane proteins by hydrostatic pressure

15:45 – 16:00 Discussion

16:00 – 16:30 Coffee Break

16:30 – 19:00 Session #4

16:30 – 17:00 Ka Yee Lee, Deciphering Differential Recognition of Phosphatidylserine-Binding Peripheral Membrane Proteins through Bound Structure Determination 

17:00 – 17:30 Jean-Baptiste Masson, Simulation-based Inference for non-parametric statistical Comparison of biomolecule dynamics

17:30 – 17:45 Sofiya Maltseva, Tryptophan fluorescence informs on how Parkinson’s Disease-associated mutants shift the equilibrium bound states of alpha-synuclein

17:45 – 18:00 Mahel Zeghouf, Membrane regulation of small GTPases signaling: a way to develop of therapeutics and chemical probes 

18:00 – 18:30 Feng-Ching Tsai and Jeriann Beiter, Molecular Insights of the Interplay between SNX9 and Phosphoinositide Lipids: Implications in Endocytosis and Macropinocytosis

18:30 – 19:00 Discussion

19:00 – 21:00 Poster Session and Dinner

Wednesday, 7 June

08:30 – 09:00 Welcome Coffee

09:00 – 12:30 Session #5

09:00 – 09:30 Suri Vaikuntanathan, Non-equilibrium Membrane transformations bounded by dissipation

09:30 – 10:00 Sylvie Roke, Quantified membrane biophysics via interfacial water imaging

10:00 – 10:30 Coffee Break

10:30 – 11:00 Jean-Baptiste Manneville, Mechanotransduction at the Golgi apparatus: regulators of rigidity and tension 

11:00 – 11:30 Andrew Callan-Jones, Anomalous diffusion of membrane tension

11:30 – 11:45 Tomasz Skora, Jamming of state-changing proteins inside macromolecularly-crowded lipid rafts

11:45 – 12:15 Jacques Prost, DC electric field effects on epitheliums

12:15 – 12:30 Discussion

12:30 – 13:30 Lunch

13:30 – 17:30 Session #6

13:30 – 14:00 Tamara Bidone, Effects of biological membranes on the slow dynamics and macromolecular diffusion of integrin 

14:00 – 14:30 Daniel Levy, Membrane composition and curvature control the catalytic activity of BmrA, an ABC transmembrane transporter

14:30 – 14:45 Cyril Favard, T-cell membrane remodelling during HIV-1 assembly : insights from single/few molecules dynamics

14:45- 15:15 Stephanie Mangenot, Membrane remodelling, curvature sensing and diffusion barriers by Septins

15:15 – 15:30 Discussion

15:30 – 16:00 Coffee Break

16:00 – 16:30 Gregory Voth, Membrane Remodeling by Proteins: Insights and Surprises from Multiscale Computer Simulation 

16:30 – 17:00 Patricia Bassereau, Combining reconstituted systems, simulations and theoretical models: a suitable approach for understanding biological membranes

17:00 – 17:30 Closing Remarks and Discussion

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