New huPreP paper accepted in Nature Communications
We’re excited that our new paper, “Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition”, has been accepted in Nature Communications. We will update this post and link to it on our...
Lab Dim Sum Outing
To celebrate the end of the semester, the lab went out to dim sum together at Ming Hin
NIH Grant awarded to study the “Integrative structural analysis of human insulin degrading enzyme”
We’re excited to announce that our NIH grant was officially funded, supporting our continued exploration of insulin-degrading enzyme through a variety of structural and dynamic investigational tools
Michelle joined the lab as an undergraduate researcher!
Michelle is a senior Biochemistry student, joining us to work on protein structural biology. Welcome, Michelle!
Maria joined the lab for a rotation project
Maria is rotating in our lab to work on a structural approach to her project with Shannon Elf. Welcome, Maria!
Nick passed his qualifying exam
Woo!
Jordan became a Fellow!
Jordan was awarded an NIH F32 Ruth L. Kirschstein Postdoctoral Fellowship to study the structural mechanisms underlying the activation and function of ExoY, a toxin produced by the bacterium Pseudomonas aeruginosa.
Published Zmp1 paper in Structure
Structural analysis of Mycobacterium tuberculosis M13 metalloprotease Zmp1 open states
Wenguang G. Liang, Jordan M. Mancl, Minglei Zhao, Wei-Jen Tang
Structure, 2021
Link