Hi, I am Jing Li, a computational biologist and chemist. I received my Ph.D degree from Biophysics and Computational Biology program at UIUC, and I was a postdoctoral associate in the laboratory of Prof. Benoit Roux at University of Chicago.

Please note that I have moved to the University of Mississippi recently, and start my own lab. This website will be expired soon. For more updated information, please follow my new group website.

My research interests are largely directed towards understanding structure-function relationship of biomolecules at the atomic level, and the molecular mechanism of the dysfunctions of these biomolecules leading to disease. To open an intelligent and efficient route to illuminate the biological mechanisms of diseases in the era of big data, my overarching goal is to bridge the gap between two fast-growing fields in computational biology, i.e., computational biophysics and genome sequencing analysis.

For more details please check my research.

 

Selected publications (For full list of publication, please check my publication):

  1. Jing Li, Jared Ostmeyer, Luis Cuello, Eduardo Perozo, Benoît Roux. Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel. Journal of General Physiology (cover article with commentary). 150(10): 1408-1420. (2018).
  2. Jing Li, Jared Ostmeyer, Eliot Boulanger, Huan Rui, Eduardo Perozo, Benoît Roux. Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation. PNAS. 114(42):11145-11150. (2017)
  3. Jing Li, Po-Chao Wen, Mahmoud Moradi, and Emad Tajkhorshid. Mechanistic view of membrane transporters through computational nanoscopy of molecular dynamics. Current Opinion in Structural Biology, 31:96-105. (2015).
  4. Jing Li, Saher A. Shaikh, Giray Enkavi, Po-Chao Wen, Zhijian Huang, and Emad Tajkhorshid. Transient formation of water-conducting state in membrane transporters. PNAS. 110: 7696-7701. (2013).

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