Selected Publications

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2020

Determinants of telomere length across human tissues.  Science 2020.  Demanelis K, Jasmine F, Chen LS, Chernoff M, Tong L, Delgado D, Zhang C, Shinkle J, Sabarinathan M, Lin H, Ramirez E, Oliva M, Kim-Hellmuth S, Stranger BE, Lai T-P,  Aviv A, Ardlie KG, Aguet F, Ahsan H, GTEx Consortium, Doherty JA, Kibriya MG, Pierce BL.  Abstract | Reprint | Full Text

Genetic determinants of reduced arsenic metabolism efficiency in the 10q24.32 region are associated with reduced AS3MT expression in multiple human tissue types. Toxicol Sci. 2020.  Chernoff M, Tong L, Demanelis K, Ahsan H, Vander Griend D, Pierce BL.

Assessing the impact of arsenic metabolism efficiency on DNA methylation using Mendelian randomization. Environ Epidemiol. 2020.  DiGiovanni A, Demanelis K, Tong L, Argos M, Shinkle J, Jasmine F, Sabarinathan M, Rakibuz-Zaman M, Sarwar G, Islam MT, Shahriar H, Islam T, Rahman M, Yunus M, Graziano J, Gamble MV, Ahsan H, Pierce BL.

Research Participants’ Attitudes towards Receiving Information on Genetic Susceptibility to Arsenic Toxicity in Rural Bangladesh. Public Health Genomics. 2020.  Tamayo LI, Lin H, Ahmed A, Shahriar H, Hasan R, Sarwar G, Eunus HM, Ahsan H, Pierce BL.

2019

Genetically Increased Telomere Length and Aging-related Traits in the UK Biobank.  J Gerontol A Biol Sci Med Sci. 2019.  Demanelis K, Tong L, Pierce BL.

Association of Arsenic Exposure with Whole Blood DNA Methylation: An Epigenome-Wide Study of Bangladeshi Adults.  Environ Health Perspect. 2019.  Demanelis K, Argos M, Tong L, Shinkle J, Sabarinathan M, Rakibuz-Zaman M, Sarwar G, Shahriar H, Islam T, Rahman M, Yunus M, Graziano JH, Broberg K, Engström K, Jasmine F, Ahsan H, Pierce BL.

A missense variant in FTCD is associated with arsenic metabolism and toxicity phenotypes in Bangladesh.  PLoS Genet. 2019.  Pierce BL, Tong L, Dean S, Argos M, Jasmine F, Rakibuz-Zaman M, Sarwar G, Islam MT, Shahriar H, Islam T, Rahman M, Yunus M, Lynch VJ, Oglesbee D, Graziano JH, Kibriya MG, Gamble MV, Ahsan H.

The contribution of parent-to-offspring transmission of telomeres to the heritability of telomere length in humans.  Hum Genet. 2019.  Delgado DA, Zhang C, Gleason K, Demanelis K, Chen LS, Gao J, Roy S, Shinkle J, Sabarinathan M, Argos M, Tong L, Ahmed A, Islam T, Rakibuz-Zaman M, Sarwar G, Shahriar H, Rahman M, Yunus M, Doherty JA, Jasmine F, Kibriya MG, Ahsan H, Pierce BL.

2018

Co-occurring expression and methylation QTLs allow detection of common causal variants and shared biological mechanisms.  Nat Commun. 2018.  Pierce BL, Tong L, Argos M, Demanelis K, Jasmine F, Rakibuz-Zaman M, Sarwar G, Islam MT, Shahriar H, Islam T, Rahman M, Yunus M, Kibriya MG, Chen LS, Ahsan H.

A study of telomere length, arsenic exposure, and arsenic toxicity in a Bangladeshi cohort. Environ Res. 2018.  Zhang C, Kibriya MG, Jasmine F, Roy S, Gao J, Sabarinathan M, Shinkle J, Delgado D, Ahmed A, Islam T, Eunus M, Islam MT, Hasan R, Graziano JH, Ahsan H, Pierce BL.

Screening for gene-environment (G×E) interaction using omics data from exposed individuals: an application to gene-arsenic interaction. Mamm Genome. 2018.  Argos M, Tong L, Roy S, Sabarinathan M, Ahmed A, Islam MT, Islam T, Rakibuz-Zaman M, Sarwar G, Shahriar H, Rahman M, Yunus M, Graziano JH, Jasmine F, Kibriya MG, Zhou X, Ahsan H, Pierce BL.

Mendelian randomization studies of cancer risk:  a literature review.  Current Epidemiology Reports 2018.   Pierce BL, Kraft P, Zhang C.

2017

Genome-wide association study of telomere length among South Asians identifies a second RTEL1 association signal. J Med Genet. 2018.  Delgado DA, Zhang C, Chen LS, Gao J, Roy S, Shinkle J, Sabarinathan M, Argos M, Tong L, Ahmed A, Islam T, Rakibuz-Zaman M, Sarwar G, Shahriar H, Rahman M, Yunus M, Jasmine F, Kibriya MG, Ahsan H, Pierce BL.

Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis. Genome Res. 2017.  Yang F, Wang J, the GTEx consortium, Pierce BL, and Chen LS

The association between telomere length and mortality in Bangladesh.  Aging (Albany NY). 2017.  Dean SG, Zhang C, Gao J, Roy S, Shinkle J, Sabarinathan M, Argos M, Tong L, Ahmed A, Islam MT, Islam T, Rakibuz-Zaman M, Sarwar G, Shahriar H, Rahman M, Yunus M, Graziano JH, Chen LS, Jasmine F, Kibriya MG, Ahsan H, Pierce BL.

2016

Sex-Specific and Time-Varying Associations Between Cigarette Smoking and Telomere Length Among Older Adults. Am J Epidemiol. 2016.  Zhang C, Lauderdale D, Pierce BL.

Telomere length measurement by a novel Luminex-based assay: a blinded comparison to Southern blot. Int J Mol Epidemiol Genet. 2016.  Pierce BL, Jasmine F, Roy S, Zhang C, Aviv A, Hunt SC, Ahsan H, Kibriya MG.

Determinants and consequences of arsenic metabolism efficiency among 4,794 individuals: demographics, lifestyle, genetics, and toxicity.  Cancer Epidemiol Biomarkers Prev 2016.  Jansen RJ, Argos M, Tong L, Li J, Rakibuz-Zaman M, Islam MT, Slavkovich V, Ahmed A, Navas-Acien A, Parvez F, Chen Y, Gamble MV, Graziano JH, Pierce BL, Ahsan H.

2015

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study. Hum Mol Genet. 2015 Sep 15;24(18):5356-66. Zhang C, Doherty JA, Burgess S, Hung RJ, Lindström S, Kraft P, Gong J, Amos CI, Sellers TA, Monteiro AN, Chenevix-Trench G, Bickeböller H, Risch A, Brennan P, Mckay JD, Houlston RS, Landi MT, Timofeeva MN, Wang Y, Heinrich J, Kote-Jarai Z, Eeles RA, Muir K, Wiklund F, Grönberg H, Berndt SI, Chanock SJ, Schumacher F, Haiman CA, Henderson BE, Amin Al Olama A, Andrulis IL, Hopper JL, Chang-Claude J, John EM, Malone KE, Gammon MD, Ursin G, Whittemore AS, Hunter DJ, Gruber SB, Knight JA, Hou L, Le Marchand L, Newcomb PA, Hudson TJ, Chan AT, Li L, Woods MO, Ahsan H, Pierce BL; GECCO and the GAME-ON Network: CORECT, DRIVE, ELLIPSE, FOCI, and TRICL.

The Genetic Architecture of Arsenic Metabolism Efficiency: A SNP-Based Heritability Study of Bangladeshi Adults.  Environ Health Perspect. 2015 Mar 13. [Epub ahead of print] PubMed PMID: 25768001.  Gao J, Tong L, Argos M, Scannell Bryan M, Ahmed A, Rakibuz-Zaman M, Kibriya MG, Jasmine F, Slavkovich V, Graziano JH, Ahsan H, Pierce BL.

Arsenic exposure, telomere length, and expression of telomere-related genes among Bangladeshi individuals.  Environ Res 2015 Jan;136:462-9.  Gao J, Roy S, Tong L, Argos M, Jasmine F, Rahaman R, Rakibuz-Zaman M, Parvez F, Ahmed A, Hore SK, Sarwar G, Slavkovich V, Yunus M, Rahman M, Baron JA, Graziano JH, Ahsan H, Pierce BL.

2014

Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians. PLoS Genet. 2014 Dec 4;10(12):e1004818.  Pierce BL, Tong L, Chen LS, Rahaman R, Argos M, Jasmine F, Roy S, Paul-Brutus R, Westra HJ, Franke L, Esko T, Zaman R, Islam T, Rahman M, Baron JA, Kibriya MG, Ahsan H.

Measurement of telomere length: a new assay using QuantiGene chemistry on a Luminex platform. Cancer Epidemiol Biomarkers Prev. 2014 Dec;23(12):2667-72.  Kibriya MG, Jasmine F, Roy S, Ahsan H, Pierce BL.

Genetic susceptibility to accelerated cognitive decline in the US Health and Retirement Study.  Neurobiol Aging. 2014 Jun;35(6):1512.e11-8.  Zhang C, Pierce BL.

2013

Arsenic metabolism efficiency has a causal role in arsenic toxicity: Mendelian randomization and gene-environment interaction.  Int J Epidemiol. 2013 Dec;42(6):1862-71.  Pierce BL, Tong L, Argos M, Gao J, Farzana J, Roy S, Paul-Brutus R, Rahaman R, Rakibuz-Zaman M, Parvez F, Ahmed A, Quasem I, Hore SK, Alam S, Islam T, Harjes J, Sarwar G, Slavkovich V, Gamble MV, Chen Y, Yunus M, Rahman M, Baron JA, Graziano JH, Ahsan H.

Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators.  Am J Epidemiol. 2013 Oct 1;178(7):1177-84.  Pierce BL, Burgess S.

2012

Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh. PLoS Genet. 2012;8(2):e1002522.  Pierce BL, Kibriya MG, Tong L, Jasmine F, Argos M, Roy S, Paul-Brutus R, Rahaman R, Rakibuz-Zaman M, Parvez F, Ahmed A, Quasem I, Hore SK, Alam S, Islam T, Slavkovich V, Gamble MV, Yunus M, Rahman M, Baron JA, Graziano JH, Ahsan H.

The effect of non-differential measurement error on bias, precision and power in Mendelian randomization studies. Int J Epidemiol. 2012 Oct;41(5):1383-93.  Pierce BL, VanderWeele TJ.