Welcome to the Prince Lab
Welcome to the Prince lab, where we use cellular, molecular, genetic, genomic and comparative approaches to study developmental processes. Our research program primarily makes use of the zebrafish, Danio rerio, which provides rapidly developing, transparent embryos. These embryos are ideal for high resolution live imaging approaches, which are helping us to understand the dynamic cellular processes that build complex structures during embryonic development. Our imaging experiments are complemented by powerful molecular genetic and transgenic tools, such as CRISPR/Cas technology, which allow us to interrogate the molecular basis of developmental processes. In addition to zebrafish, Prince lab members use little skate and other species in comparative studies. Please take a look around our pages to learn more about our ongoing studies on the neural crest, the anterior lateral line, and the pronephros.
NEWS AND EVENTS
Prince lab represents at Midwest Zebrafish Meeting
Lab members Elaine and Clare attended the 2022 Midwest Zebrafish Meeting this past weekend! They traveled to the Ohio State University in Columbus, Ohio to chat science, hear exciting talks, and present their own research. Elaine gave a talk entitled "Quest for the...
Prince lab paper makes cover of Developmental Biology!
The lab's recent work investigating the role of Cdx4 in zebrafish trunk neural crest development generated not only spectacular science but spectacular images! A confocal microscopy image of the neural crest cells (magenta) in a chimeric cdx4 mutant embryo made the...
Cdx4 paper is published!
Results from the lab's most recent project investigating the function of the homeodomain transcription factor Cdx4 in posterior neural crest development have just been published in the journal Developmental Biology. The paper, entitled "Zebrafish Cdx4 regulates neural...