Welcome to the Prince lab, where we use cellular, molecular, genetic, genomic and comparative approaches to study developmental processes. Our research program primarily makes use of the zebrafish, Danio rerio, which provides rapidly developing, transparent embryos. These embryos are ideal for high resolution live imaging approaches, which are helping us to understand the dynamic cellular processes that build complex structures during embryonic development. Our imaging experiments are complemented by powerful molecular genetic and transgenic tools, such as CRISPR/Cas technology, which allow us to interrogate the molecular basis of developmental processes. In addition to zebrafish, Prince lab members use little skate and other species in comparative studies. Please take a look around our pages to learn more about our ongoing studies on the neural crest, the anterior lateral line, and the pronephros.
NEWS AND EVENTS
Prince lab paper makes cover of Developmental Biology!
The lab’s recent work investigating the role of Cdx4 in zebrafish trunk neural crest development generated not only spectacular science but spectacular images! A confocal microscopy image of the neural crest cells (magenta) in a chimeric cdx4 mutant embryo made the cover of the December 2021 edition of Developmental Biology. The image accompanies the lab’s most recent paper “Zebrafish Cdx4 regulates neural crest cell specification and migratory behaviors in the posterior body”, which you can check out here.
Cdx4 paper is published!
Results from the lab’s most recent project investigating the function of the homeodomain transcription factor Cdx4 in posterior neural crest development have just been published in the journal Developmental Biology. The paper, entitled “Zebrafish Cdx4 regulates neural crest cell specification and migratory behaviors in the posterior body” was spearheaded by recent graduate Dr. Manny Rocha and features contributions from many lab members. Check it out here!
Vicky is elected President of the Society for Developmental Biology!
As of Monday, Vicky is now the President-elect of the Society for Developmental Biology. The news was announced at the first day of this year’s SDB Annual Meeting. Get excited for SDB 2023, which Vicky will be organizing here in Chicago!