Welcome to the Prince lab, where we use cellular, molecular, genetic, genomic and comparative approaches to study developmental processes. Our research program primarily makes use of the zebrafish, Danio rerio, which provides rapidly developing, transparent embryos. These embryos are ideal for high resolution live imaging approaches, which are helping us to understand the dynamic cellular processes that build complex structures during embryonic development. Our imaging experiments are complemented by powerful molecular genetic and transgenic tools, such as CRISPR/Cas technology, which allow us to interrogate the molecular basis of developmental processes. In addition to zebrafish, Prince lab members use little skate and other species in comparative studies. Please take a look around our pages to learn more about our ongoing studies on the neural crest, the anterior lateral line, and the pronephros.
NEWS AND EVENTS
Vicky gives a talk at BSDB
At the April 2021 British Society for Developmental Biology (BSDB) Meeting, lab head Dr. Vicky Prince gave an excellent 12 minute talk on previous grad student Dr. Ana Beiriger’s thesis work on efferent neuron migration. Watch the talk, entitled “Genetic and cellular mechanisms that distinguish zebrafish hindbrain efferent neuron populations” here or over on our Research page!
Manny successfully defends his thesis!
Congratulations to Dr. Manny Rocha, who expertly defended his thesis entitled “Cdx4 regulates the development of neural crest cells in the posterior body of zebrafish embryos” and is now the Prince lab’s newest PhD! Manny led the Prince lab’s recent research into neural crest patterning and regionalization. During his time in the lab, he has been a wonderful collaborator and a mentor to many younger lab members. He (and his canine companion Butters) will be sorely missed, but we wish him luck in his new endeavor as an analyst at Driehaus Capital Management, where he’ll be working for their life sciences fund!
Izzy’s lateral line innervation review is published!
An article by lab undergrad Izzy Cisneros reviewing the comparative anatomy of fish lateral line innervation patterns was just published in UChicago’s undergraduate research journal, Scientia. Check out this thorough review (with some awesome figures) on p. 24 of the Winter 2021 issue of Scientia here!