
Welcome to the Prince lab, where we use cellular, molecular, genetic, genomic and comparative approaches to study developmental processes. Our research program primarily makes use of the zebrafish, Danio rerio, which provides rapidly developing, transparent embryos. These embryos are ideal for high resolution live imaging approaches, which are helping us to understand the dynamic cellular processes that build complex structures during embryonic development. Our imaging experiments are complemented by powerful molecular genetic and transgenic tools, such as CRISPR/Cas technology, which allow us to interrogate the molecular basis of developmental processes. In addition to zebrafish, Prince lab members use little skate and other species in comparative studies. Please take a look around our pages to learn more about our ongoing studies on the neural crest, the anterior lateral line, and the pronephros.



NEWS AND EVENTS
Lab undergrads write about axolotls and vaccines
Undergraduate students Clare, Izzy, & Sweta (now an MD/PhD student at UPenn) have been prolific science writers and editors in Spectrum blog of the Triple Helix, UChicago’s undergraduate science journalism organization. Check out their articles about axolotl regeneration (written by Clare Booth and edited by Izzy Cisneros) and the search for a COVID-19 vaccine (written by Sweta Narayan). And get excited for Izzy’s upcoming review of lateral line nerves in Scientia, the Triple Helix’s undergraduate research journal!
Prince Lab twitter account hatches
Follow us on our newest social media platform at @PrinceLab_UofC, run by graduate student Vish!
Endoderm development paper published
Check out the lab’s most recent publication “Midline morphogenesis of zebrafish foregut endoderm is dependent on Hoxb5b” by former Prince Lab research associate Gokhan Dalgin: https://authors.elsevier.com/a/1cDXM2mzTT1C5.