Ongoing & Available Projects in the Lab
Epigenetic Regulation
– Chromatin remodeling
– Genome architecture and mapping
– Hydroxymethylation and methylation
– Transcriptional modification
Hypoxia Program
– Epigenetics
– HIF-1, HIF-2, and TET1 regulation
– Metabolic regulation
– Preclinical drug studies
Biomarker Development
– Machine learning
– Outcome predictions
– Risk stratification
– Therapeutic guidance
Data Commons Development & Mining
– Genomic Data Commons
– International Neuroblastoma Research Group
– International Soft Tissue Sarcoma Database Consortium
– Pediatric Cancer Data Commons
Major Approaches & Models We Commonly Use
Bioinformatics
Cell lines
Data mining
Functional genomics
Molecular biology
Primary human cells and patient samples
Lab Members Are Encouraged to Gain Both Wet Lab & Dry Lab Expertise
