Staff

As the Facility just opened in February of 2017, we currently have a staff of five.

Richard Freifelder, Ph.D.

Richard Freifelder, Ph.D.

Cyclotron Facility Program Director

Richard Freifelder, Ph.D. is the Program Director of the Facility.  Dr. Freifelder has been a member of the University of Chicago community since August of 2014.  He designed and managed the $8.4M Cyclotron Facility construction project at Chicago which included a new IBA 18/9 accelerator, 5 cleanrooms, and was also involved in the design and construction of Chicago’s small animal imaging Facility, iSAIRR. Previously he worked at the University of Pennsylvania for 24 years.  For those first 10 years, he was a member of the Physics and Instrumentation Group under Joel Karp, Ph.D. doing PET scanner design, front end electronics, performance measurements, and scintillator investigations.  In 2000 he split his time between instrumentation and work in Penn’s Cyclotron Facility.  In 2002, he moved permanently to the Cyclotron and became the Facility Manager of the Cyclotron until his retirement from Penn in 2014.  During that time, he supported 10 IND drugs, supervised a staff of 10 employees, and managed 4 different construction projects – including an $8.5M expansion of the facility from 5,000 square feet to 8,000 square feet.  That 2008-2010 project included the installation of two additional vaults, a second cyclotron, four ISO Class 8 cleanrooms, and auxiliary space.  At the completion of that project, he installed 6 hot cells and filed an ANDA for the clinical production of 18F-FDG.  The filing was approved with no 483 deficiencies.   Prior to his coming to Penn, Dr. Freifelder spent 5 years working at the Gesellschaft für Schwerionenforschung (GSI) in Darmstadt Germany on heavy-ion and relativistic heavy-ion research.  His focus was on detectors and electronics.  He received his Ph.D. in Experimental Nuclear Physics from Stony Brook University in 1985.

Swapna Chitneni, Ph.D., R.PH.

Swapna Chitneni, Ph.D., R.PH.

Head of Quality Assurance

Swapna Chitneni is the Quality Assurance Manager of the facility. Swapna has a Ph.D. in Pharmaceutical Sciences from KU Leuven, Belgium and is also a licensed pharmacist in the state of Illinois. She joined the University of Chicago in July 2024 and is trained in operating the Cyclotron at the facility. She participates in clinical and preclinical productions at the facility performing dispensing, quality control of the final product and quality assurance by making sure all the specifications are met before release of the final product. She performed internal audits on the different SOPs of the facility. Previously, she had a 5-year experience working as a Pharmacist at Walgreens in Illinois and North Carolina and at an independent pharmacy in North Carolina. She has more than 2-year Postdoctoral fellowship experience including working at a CRO in a cGMP facility performing Quality assurance and Quality control release testing of raw materials and APIs and working at University of Virginia on characterization of ultra-fast capillary electrophoresis (CE) combined with laser induced fluorescence (LIF) for real-time neurotransmitter analysis. During her Ph.D., she worked on Capillary electrophoresis (CE) method development and validation for active anabolite analysis of anti-HIV drug didanosine in peripheral blood mononuclear cells (PBMCs) using CE-FD (fluorescence detection). She also performed impurity profiling and stability studies of antibiotics using HPLC.
Lucas gonzalez, B.S.

Lucas gonzalez, B.S.

Quality Assurance Specialist, Cyclotron Operator

Lucas Gonzalez, B.S. is our most recent addition to our staff.  Lucas has a degree in Chemical Engineering (2016) from the University of Illinois, Urbana-Champaign.  After receiving his degrees, he enlisted in the Navy where he served for 5 1/2 years.  He was Electronics Technician Nuclear, 1st Class.  He trained on MTS635, one of the oldest high pressure reactors still in service.  From there, he was stationed on the USS Theodore Roosevelt (aircraft carrier) CVN71 out of San Diego.  He was a qualified reactor operator and reactor technician on the ship’s A4W reactor (the ship has two reactors).  He was deployed twice to the 7th Fleet (South China Seas) with Carrier Strike Group 9.  After that, the ship’s home port was changed to Bremerton, WA where he participated in overhauling the ship’s rod control system.  He was honorably discharged in August 2022.  He moved back to the Chicago area and joined the Cyclotron Facility in April 2023.  His move from the Navy to Radiopharmaceutical Product and Quality Assurance/Control has been seamless.

Kaustab Ghosh, Ph.D.

Kaustab Ghosh, Ph.D.

Radiochemist

Dr. Ghosh received his Ph.D. in Chemistry from the University of Calcutta where he focused on radiometals.  He worked at the Saha Institute of Nuclear Physics after his Ph.D.  He then moved to the Delft Institute of Technology in the Netherlands for a year.  There his work focused on 166Ho production used with microspheres for the treatment of patients with liver cancer.  He continued his overseas experience at RIKEN in Japan, where he worked for just under a year and a half.  He used his experience in radiometals to work on the production of  211At and other solid target isotopes.  He then returned to India and was involved in clinical production of drugs with a private company.  His work included running the cyclotron, Quality Control, and production of drugs.  He joined our Facility in June of 2021.

Santosh Alluri, Ph.D.

Santosh Alluri, Ph.D.

Radiochemist

Dr. Santosh Alluri is the newest member of our Facility. He comes to the University of Chicago from Yale University.  There he worked on radiotracer development involving medicinal chemistry, organic synthesis, radiochemical synthesis, metabolism measurement and analysis, pharmacokinetics and pharmacodynamics by PET, and clinical research. He is a qualified radiopharmaceutical production (GMP) chemist for clinical research. He has operated a variety of nucleophilic substitution 18-F modules and also worked on 11-C compounds.  In addition, he has operated cyclotrons for isotope manufacturing and delivery.

Former Staff Members:

Mohammed Parvez Bhuiyan, Ph.D.

Associate Director, Radiochemist

Anna Kucharski, BS, MBA

Quality Control Specialist, Radiochemist

Facility Members:

Satish Chitneni, Ph.D., R.Ph.

Satish Chitneni, Ph.D., R.Ph.

Faculty Director of the Cyclotron Facility and Associate Professor, Department of Radiology

Satish Chitneni, Ph.D., R.Ph. is an Associate Professor in the Department of Radiology.  Dr. Chitneni received his pharmacy training in India and subsequently received his Ph.D. at the Katholieke Universiteit of Leuven, in Belgium.  He was an Assistant and then Associate Professor from 2011 until 2023 at Duke University in Durham, North Carolina.   He joined the University of Chicago in 2023.  His research interests are wide ranging and he has used a variety of radioisotopes such as fluorine-18 (18F), carbon-11 (11C), radioiodines (125I, 131I, 124I), zirconium-89 (89Zr), and lutetium-177 (177Lu).  He has worked on issues in oncology, hypoxia, glutamine metabolism, PSMA research with beta and alpha emitters, Gliomas, MDM2, and other areas.  

Chin-Tu Chen, PH.D.

Chin-Tu Chen, PH.D.

Professor, Department of Radiology

Chin-Tu Chen, Ph.D. is a Professor in the Department of Radiology.  Dr. Chen has been a long-time advocate and spokesperson for the Cyclotron Facility.  Dr. Chen bridges the time period from the CS-15 in the 1980s and 1990s  to the IBA Cyclone® now.  He has been key in re-establishing a working, modern, Cyclotron Facility at the University of Chicago and putting together a PET radiochemistry program.  His research interests are wide ranging and include: image analysis, image corrections, PET/SPECT instrumentation, small animal imaging, radiochemistry, biochemistry and microbiology, and finally clinical trials.  Without Chin-Tu Chen’s enthusiasm, constant support, and endless energy, the new Cyclotron Facility at the University of Chicago would not have been possible.

Steven Montner, M.D.

Steven Montner, M.D.

Professor and Chairman, Department of Radiology

Steven Montner, M.D., is the Chair of the Department of Radiology.  He specializes in pulmonary imaging, analyzing and interpreting chest radiographs and CT scans for thoracic disease and has expertise in interstitial lung disease.  He is active in the Radiological Society of North America and the Society of Thoracic Imaging.  Even before taking over the Chairmanship, he was integrally involved in the operations, budgeting, management, planning and the programmatic goals of the Facility. He has shown enthusiastic support for our operations.  Dr. Montner is the immediate past president of the medical staff organization.  

Aytekin Oto, M.D., M.B.A.

Aytekin Oto, M.D., M.B.A.

Chairman, Department of Radiology

Aytekin Oto, M.D., M.B.A. is the Past Chair of the Department of Radiology and Professor of Radiology and Surgery.  He is now Dean for Clinical Affairs at the University of Chicago and head of the faculty practice plan.  His guidance and assistance in running the Cyclotron Facility are sorely missed.  He was key in establishing the Facility’s ability to produce and distribute radio-pharmaceutics to facilities and hospitals not only in the Greater Chicago area but also to locations throughout the Upper Midwest of the United States.  

DAVID PAUSHTER, M.D., FACR

DAVID PAUSHTER, M.D., FACR

Past Chair, Department of Radiology

David Paushter, M.D., FACR, is the past Chair of the Department of Radiology.  His support was critical to re-establishing the Facility.    Dr. Paushter worked to establish internal and external advisory committees and helped to make not only the UChicago medical community aware of the Cyclotron Facility but also the medical community in the greater Chicago area.