The University of Chicago

Missiakas Lab

Latest Presentations

“An autocatalytic peptidase modulates surface protein display and cytokinesis in S. aureus” – Dr. Shafiul Azam

“Host-Pathogen Interplay in S. Aureus Nasopharynx Colonization.” – Dr. Yunys Perez Betancourt

Latest Publications

January 4, 2024

Ibrahim AM, Azam MS, Schneewind O, Missiakas D. Processing of LtaS restricts LTA assembly and YSIRK preprotein trafficking into Staphylococcus aureus cross-walls. mBio. 2024 Jan 4; Epub ahead of print. PMID: 38174934.

July 15, 2023

Bernardino PN, Bhattacharya M, Chen X, Jenkins J, Missiakas D, Thammavongsa V. A humanized monoclonal antibody targeting protein a promotes opsonophagocytosis of Staphylococcus aureus in human umbilical cord blood. Vaccine.

April 11, 2023

Bobrovskyy, M., Chen, X., & Missiakas, D. (2023). The Type 7b Secretion System of S. aureus and Its Role in Colonization and Systemic Infection. Infection and Immunity, e00015-23.

March 27, 2023

Chen, X., Gula, H., Pius, T., Ou, C., Gomozkova, M., Wang, L. X., … & Missiakas, D. (2023). Immunoglobulin G subclasses confer protection against Staphylococcus aureus bloodstream dissemination through distinct mechanisms in mouse models. Proceedings of the National Academy of Sciences, 120(14), e2220765120.

January 13, 2023

Oh, S. Y., Chateau, A., Tomatsidou, A., Elli, D., Gula, H., Schneewind, O., & Missiakas, D. (2023). Modeling gastrointestinal anthrax disease. Research in Microbiology, 104026.

September, 2022

Bobrovskyy, M., Oh, S. Y., & Missiakas, D. (2022). Contribution of the EssC ATPase to the assembly of the type 7b secretion system in Staphylococcus aureus. Journal of Biological Chemistry, 298(9).

August 23, 2022

Tomatsidou, A., Krunic, M., & Missiakas, D. (2022). Contribution of TagA-Like Glycosyltransferases to the Assembly of the Secondary Cell Wall Polysaccharide in Bacillus anthracis. Journal of Bacteriology, 204(9), e00253-22.

January 20, 2022

Chen, X., Schneewind, O., & Missiakas, D. (2022). Engineered human antibodies for the opsonization and killing of Staphylococcus aureus. Proceedings of the National Academy of Sciences, 119(4).

Yunys Pérez Betancourt

“The molecular battleground of S. aureus colonization: insights into host-pathogen interaction.”

Miaomiao Shi

SpA: B cell superantigen extraordinaire

Tonu Pius

“Preclinical Development of a Vaccine Against Staphylococcus aureus”

Shafiul Azam

“A SecA-Associated Protease Modulates Protein Translocation in S. aureus”

Announcements

Congratulations to Maksym Bobrovskyy who accepted a position at the University of South Florida.

 

Congratulations to Xinhai Chen who accepted a position at Shenzhen Bay Laboratory.

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