Pd-Catalyzed Intramolecular α‑Allylic Alkylation of Ketones with Alkynes: Rapid and Stereodivergent Construction of [3.2.1] Bicycles
Our research interests is to harness the power of transition-metal catalysts to address the challenges in the arena of chemoselectivity and multi-step synthesis. Our research philosophy is guided by three questions:
1) What would be the most efficient way to introduce functional groups into (small or large) organic molecules?
2) What would be the most efficient method to synthesize various molecular skeletons (bridged or fused rings) with high complexity?
3) What would be the most efficient strategy to access mutiple structurally complicated and biologically important natural products and their analogues in a rapid fashion?
We are delighted to announce that Yan Xu with the publication “Deacylative Transformations of Ketones via Aromatization-Promoted C–C Bond Activation” in Nature is one of the 45 finalists for the Reaxys PhD Prize 2019!
Jun 2019 Lin and Jianchun just defended the Ph.D. thesis! Apr 2019 Lin Deng and Jianchun Wang have both been awarded the highly competitive "Chinese Government Award for Outstanding Self-Financed Students Abroad". Congratulations to both of them!
Aug 2018 Dr. Yan Xu successfully defended his Ph.D. thesis. Congratulations to Yan.