Pd-Catalyzed Intramolecular α‑Allylic Alkylation of Ketones with Alkynes: Rapid and Stereodivergent Construction of [3.2.1] Bicycles
Our research interests is to harness the power of transition-metal catalysts to address the challenges in the arena of chemoselectivity and multi-step synthesis. Our research philosophy is guided by three questions:
1) What would be the most efficient way to introduce functional groups into (small or large) organic molecules?
2) What would be the most efficient method to synthesize various molecular skeletons (bridged or fused rings) with high complexity?
3) What would be the most efficient strategy to access mutiple structurally complicated and biologically important natural products and their analogues in a rapid fashion?
Congratulations to Renhe and Cole! Renhe won Elizabeth R. Norton Prize for Excellence in Research in Chemistry! Cole has been awarded for Gerhard Closs Teaching Award in Organic Chemistry!
Congratulation to Alex for his successfully defense! He will soon start his next journey in AbbVie! We had a celebration party in person for the first time in two years!