The University of Chicago

Dong Research Group

Welcome to Dong Group!

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Group News

Our JACS Video Byte: Escape from Palladium: Nickel-Catalyzed Catellani Annulation by Jingfeng Huo, Yue Fu, Melody J. Tang, Peng Liu, and Guangbin Dong is now available on ACS YouTube channel!

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Research Highlights

Ortho-C–H Methoxylation of Aryl Halides Enabled by a Polarity Reversed N–O Reagent

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Research Highlights

Modular synthesis of 1,2-azaborines via ring-opening BN-isostere benzannulation

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Research Highlights

Rhodium-Catalyzed Diastereo- and Enantioselective Divergent Annulations between Cyclobutanones and 1,5-Enynes: Repaid Construction of Complex C(sp3)-Rich Scaffolds

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Research Highlights

Iridium-Catalyzed Intramolecular β-C–H Alkenylation of Ketones with Alkynes via a Hydride-Transfer Approach

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Research Directions

Our research interests is to harness the power of transition-metal catalysts to address the challenges in the arena of chemoselectivity and multi-step synthesis. Our research philosophy is guided by three questions:

1) What would be the most efficient way to introduce functional groups into (small or large) organic molecules?

2) What would be the most efficient method to synthesize various molecular skeletons (bridged or fused rings) with high complexity?

3) What would be the most efficient strategy to access mutiple structurally complicated and biologically important natural products and their analogues in a rapid fashion?

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