by sarahcmay | Dec 31, 2024 | Publications
We recently published a new research article, “12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice,” in JCI Insight. Postdoctoral fellow Titli Nargis, PhD, led the study, which showed that VLX-1005 (a human-specific 12-LOX...
by sarahcmay | Jul 16, 2024 | Awards
Postdoctoral fellow Charanya Muralidharan (far right) won a top presentation award at the 2024 Midwest Islet Club meeting, which took place at the University of Chicago. The title of her talk was “Inhibition of the PERK (eukaryotic initiation factor 2α kinase)...
by sarahcmay | Jul 16, 2024 | Publications
The Mirmira Lab recently published a new manuscript in Journal of Clinical Investigation entitled “Inhibition of the eukaryotic initiation factor-2-α kinase PERK decreases risk of autoimmune diabetes in mice.” Led by postdoctoral fellow Charanya...
by sarahcmay | Mar 15, 2024 | Awards
At this year’s Janet Rowley Research Day at the University of Chicago, postdoctoral fellow Titli Nargis, PhD, won an award for her top abstract “12-Lipoxygenase Inhibitor Delays Diabetes Development in a Humanized Mouse Model.” Graduate student Andy Anderson received...
by sarahcmay | Jan 24, 2024 | Publications
The Mirmira lab, led by first author Batoul Hammoud, MD, published a new study in Endocrinology demonstrating the effects of polyamine depletion by DENSpm on mice. Unlike DFMO (see previous study), DENSpm had only modest effects on type 1 diabetes outcomes in NOD mice...
