Mirmira Lab Trainees Take Home Abstract and Poster Awards from 2024 Janet Rowley Research Day
At this year’s Janet Rowley Research Day at the University of Chicago, postdoctoral fellow Titli Nargis, PhD, won an award for her top abstract “12-Lipoxygenase Inhibitor Delays Diabetes Development in a Humanized Mouse Model.” Graduate student Andy Anderson received...
New Publication: “Discordant Effects of Polyamine Depletion by DENSpm and DFMO on β-cell Cytokine Stress and Diabetes Outcomes in Mice”
The Mirmira lab, led by first author Batoul Hammoud, MD, published a new study in Endocrinology demonstrating the effects of polyamine depletion by DENSpm on mice. Unlike DFMO (see previous study), DENSpm had only modest effects on type 1 diabetes outcomes in NOD mice...
New Publication: “Leukotriene B4 Receptor 2 Governs Macrophage Migration During Tissue Inflammation”
The Mirmira lab published a new study in Journal of Biological Chemistry. First author Ebru Ermis, a former lab undergraduate, found that leukotriene B4 receptor 2 (or BLT2) promotes macrophage migration during inflammation in mice and zebrafish. The next step is to...
New Publication: “Inhibition of Polyamine Biosynthesis Preserves β Cell Function in Type 1 Diabetes”
The Mirmira Lab, together with investigators at Indiana University School of Medicine, published a new study in Cell Reports Medicine that investigates α-difluoromethylornithine (DFMO) as a potential therapeutic for type 1 diabetes. In a randomized controlled trial of...
Kierstin and Jacob Present at HIRN 2023 Annual Investigator Meeting
Mirmira Lab graduate student Kierstin Webster and postdoctoral fellow Jacob Enriquez presented at the Human Islet Research Network (HIRN) meeting held September 19-21 in Washington, D.C. Kierstin reported that "Human Islets Exhibit Sex Differences in Transcriptional...
Dr. Mirmira Receives the Albert Renold Award at ADA 2023
Dr. Mirmira received the Albert Renold Award at the 2023 American Diabetes Association's Scientific Sessions in San Diego, CA. This prestigious award recognizes Dr. Mirmira's outstanding achievements in mentoring and fostering scientific communities to enhance...
Christian Receives Presidential Poster Award at ENDO 2023
Graduate student Christian Checkcinco was selected to receive a Presidential Poster Award at ENDO 2023 for his poster entitled "The G protein coupled receptor GPR31 promotes islet inflammation and diabetes." He gave a brief overview of his research findings during a...
Charanya Wins Outstanding Abstract Award at ENDO 2023
Postdoctoral fellow Charanya Muralidharan received an Outstanding Abstract Award at the Endocrine Society's ENDO 2023 meeting. The title of her talk was "Blocking the maladaptive integrated stress response increases immunosuppressive PD-L1 in pancreatic beta cells."...
Andy Secures NIH F31 Predoctoral Fellowship
Graduate student Andy Anderson has obtained an F31 predoctoral fellowship from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Andy's research focuses on a rare protein modification known as hypusination, which is important for beta cell...
Andy and Kierstin Receive Poster Awards at Chicago Diabetes Day
Graduate students Andy Anderson (second from left) and Kierstin Webster (third from left) received awards for their top-scoring poster presentations at Chicago Diabetes Day. This annual event is sponsored by the University of Chicago's Diabetes Research & Training...