Knapp Center for Biomedical Discovery 900 E 57th Street Room 1230C Chicago, IL 60637
The Genomics Core Facility is located in the Knapp Center for Biomedical Discovery and directed by Dr. Yoav Gilad, Professor in the Department of Human Genetics. In addition to Dr. Gilad the core has a dedicated staff of 11 people including 3 PhD level scientists. The major services provided are Next Generation DNA Sequencing, DNA microarrays and Sanger DNA Sequencing. For single cell applications the Facility operates a 10X Genomics Chromium Controller, a Takara iCell 8 and a MissionBio Tapestri to generate NGS libraries.
Next Generation Sequencing: The Facility utilizes Illumina MiSEQ, NextSeq500, HiSEQ 4000 and NovaSEQ6000 instruments to perform DNA sequencing (whole genome, ChIP, Exome and other) and RNA sequencing services.
Microarray Analysis: The Facility owns and operates an Illumina IScan
Sanger DNA Sequencing and Genotyping:The Facility operates two Applied Biosystems 3730XL and one 3130XL genetic analyzers for small and high throughput users.
Other services offered include technical consultations, nucleic acid purification, sample processing and library construction. Plate and micro-volume readers are provided for client use.
The Genomics Core is supported by the Cancer Center Support Grant (P30 CA014599). It may be identified in publications as The University of Chicago Functional Genomics (RRID:SCR_019196).
