Gross Pathology Manual

By The University of Chicago Department of Pathology

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  • UChicago Gross Pathology
    • Overview (Protected)
    • Resident Responsibilities (Protected)
    • Histology Pickups (Protected)
    • General Specimen Evaluation (Protected)
    • Gross Photography
  • Bone & Soft Tissue
    • Bone & Soft Tissue Biopsies
    • Crystals (gout, pseudogout)
    • Lipoma
    • Osteochondroma
    • Soft Tissue Tumor
    • Neurofibroma
    • Bone Tumor
    • Limb Amputation for Tumor
    • Limb Amputation (not tumor)
    • Digit or Transmetatarsal Amputation
    • Arthroplasty
    • Orthopedic Hardware
  • Breast
    • Breast Core Biopsies
    • Breast Implants & Expanders
    • Lumpectomy
    • Mastectomy
    • Prophylactic and Gender Affirmation Mastectomy
    • Reduction / Reconstruction
    • Breast Sentinel Node
  • GI & Liver
    • GI Biopsies & EMRs
    • Appendix
    • Gallbladder
    • Esophagus (neoplastic)
    • Stomach (non-neoplastic)
    • Stomach (neoplastic)
    • Stomach (prophylactic)
    • Bowel (non-neoplastic)
    • Bowel (trauma)
    • Small Bowel (neoplastic)
    • Colon & Rectum (neoplastic)
    • Ulcerative Colitis
    • Crohn’s Disease
    • Liver Core Biopsy
    • Liver Wedge Biopsy
    • Liver Partial Resection
    • Liver Explant
    • Pancreas (Whipple)
    • Pancreas (Distal)
    • Omentum – GI
    • Cytoreduction / HIPEC
  • GU & Renal
    • Adrenal Gland
    • Kidney Biopsy
    • Nephrectomy (transplant or non-neoplastic)
    • Nephrectomy (neoplastic)
    • Partial Nephrectomy (neoplastic)
    • Kidney (trauma)
    • Ureterectomy (or Nephroureterectomy)
    • Bladder: TURBT
    • Bladder: Cystectomy or Cystoprostatectomy
    • Prostate: TURP
    • Prostate: Core Biopsies
    • Prostate: Prostatectomy
    • Testis
    • Penectomy
    • Vas Deferens (Sterilization)
    • Foreskin or Hernia Sac
  • Gyne
    • Cervical / Vaginal / Vulvar Biopsies
    • Cervix (LEEP or Cone)
    • Radical Trachelectomy
    • Endocervical / Endometrial Curettage or Biopsy
    • Fallopian Tube
    • Ovary, Benign
    • Ovary, Borderline / Malignant
    • Myomectomy
    • Uterus, Benign
    • Uterus, Cervical Cancer
    • Uterus, Endometrial Cancer
    • Uterus, Endometrial Hyperplasia
    • Uterus, Lynch Syndrome
    • Uterus, BRCA
    • Uterus, Post-Partum
    • Vulvectomy
    • Omentum – GYN
  • Heme
    • Bone Marrow
    • Lymphoma Workup
    • Spleen
  • Head & Neck
    • Oral Biopsies
    • Tonsils & Adenoids
    • Sinus Contents
    • Nasal Septum
    • Neck Dissections
    • Tongue / Mucosal Excision
    • Sentinel Lymph Nodes for H&N Squamous Cell Carcinoma
    • Salivary Gland
    • Larynx
    • Mandible
    • Maxilla
    • Ear & Temporal Bone
    • Eye Enucleation
    • Thyroid
    • Parathyroid
  • Neuro
    • Neuro Biopsy or Resection
    • Muscle Biopsy
    • Nerve Biopsy
    • Eye Enucleation
    • Temporal Artery Biopsy
    • Discectomy/Laminectomy
    • Neurofibroma
  • Peds & Perinatal
    • Fetus
    • Products of Conception
    • Placenta (singleton)
    • Placenta (twin or triplet)
    • Placentas in Fetal Autopsies
    • Hirschsprung Disease
    • Neuroblastoma
    • Kidney Tumors
  • Skin
    • Skin Excision
    • Punch Biopsy
    • Shave Biopsy
  • Thorax & Peritoneum
    • Heart Biopsy
    • Native Heart Valves
    • Prosthetic Heart Valves
    • Heart Explant
    • Cardiac Tumor
    • Lung Biopsy
    • Lung Wedge Biopsy
    • Lung Resection for Tumor
    • Lung Explant
    • Pleura
    • Peritoneal Mesothelioma
    • Thymus
  • Gross Only
  • Rush / Priority Cases
  • Special Processing
    • Decalcification
    • Cytogenetics
    • Electron Microscopy
    • Immunofluorescence
    • Molecular Testing
    • Snap Freezing
    • Tissue Banking
    • Small Tissue Pieces
    • Core Biopsy (General / NOS)
  • Intraoperative (Frozens)
    • Telepathology
    • Intraoperative Consultation General Guidelines (Protected)
    • Microlaryngoscopic Biopsies
    • Mucosal Excisions for Frozen
    • Parathyroid Frozen
    • Salivary Gland, Intraoperative
    • Neuro Intraoperative Consultation
    • Hirschsprung for Frozen
    • Ovary, Intraoperative
    • Uterus, Intraoperative
    • Donor Liver Biopsy
    • Breast Sentinel Node for Frozen
  • Contact Us

Special Processing

Special processing techniques, both in the gross room and subsequent labs, include:

  • Decalcification
  • Cytogenetics
  • Electron Microscopy
  • Immunofluorescence
  • Molecular Testing (NGS)
  • Snap Freezing
  • Tissue Banking for Research
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Helpful Links

  • AAPA grossing guidelines
  • CAP cancer protocols
  • UChicago Pathology Department
  • WHO Classification of Tumours

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Nicole Cipriani, MD Nicole.Cipriani@bsd.uchicago.edu

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