Auto text: “Insert FAP Colon”

These patients have an increasing risk of colorectal adenocarcinoma as they get older.  If a colorectal cancer is present, then the specimen should be treated as a cancer resection specimen (with additional sampling of the largest polyps). If no cancer is present then:

1. Photograph the entire specimen at low power as well as representative higher power views of the largest/most grossly worrisome polyps.
2. Note the presence or absence of perirectal skin at the distal margin (total abdominal colectomy versus proctocolectomy).
3. Estimate the total number of colorectal polyps and describe their distribution and size range.
4. Sample the 10 largest colorectal polyps.
5. Note the presence or absence of any polyps grossly worrisome for cancer (and if present, sample entirely).
6. Carefully inspect the attached segment of distal ileum and submit any visible polyps, or a random section if no lesion is visible.
7. Submit a few pericolic lymph nodes.
8. Submit representative sections of the appendix. 

NOTE: No snap frozen tissue is needed. If tumor banking is requested then many of the polyps can be banked (except those worrisome for invasive tumor)

Last updated by: GI group & Kwon on 7/16/2025